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EnlargeAMLODIPINE MEDICA
Amlodipine besilate equivalent to 5 and 10 mg amlodipine.
A calcium antagonist which inhibits transmembrane influx of the calcium ions in cardiac and vascular smooth muscles.
Indicated for treatment of:
• Hypertension
• Stable angina pectoris
Advantages:
- high efficacy in mild, moderate, and severe hypertension
- less angina episodes
- appropriate for treatment of younger and older adults
- single intake providing 24-hour effect
- successfully combined with thiazide diuretics, beta blockers, and АСЕ inhibitors
- good safety profile
Mechanism of action:
- direct relaxant effect on vascular smooth muscles thereby lowering arterial pressure and reducing cardiac load.
- dilating coronary arteries and arterioles thereby improving coronary blood flow and increasing myocardial oxygen supply.
